By Glenn Haumann
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Extra info for 101 Other Uses for a Condom
The latest results of the Scandinavian randomized study comparing radical surgery versus watchful waiting concluded that there was no beneﬁt from radical prostatectomy in terms of metastasis-free survival and disease-speciﬁc survival in patients over 65 years old (Bill-Axelson et al. 2008). Note, however, that in this study patients were not subjected to prostate speciﬁc antigen (PSA) monitoring. The three main strategies for PCa treatment of elderly patients are conformal radiotherapy, brachytherapy and active watchful waiting.
83 ng/mL. Disease progression occurred in 16/48 (33 %). Of these, 4 had local recurrence in the untreated lobe and 4 bilaterally; 6 developed metastases, and 2 had rising PSA without local recurrence or radiologically proven metastasis. Progression-free survival rates (PFSR) at 12, 18, and 24 months were 83 %, 64 %, and 52 %, respectively. Severe incontinence occurred in 4/48 (8 %), with 8/48 (17 %) requiring one pad a day, and 36/48 (75 %) were pad-free. 8. Osteitis occurred in two patients. Conclusion HIFU is now used to treat PCa in clinical practice and in different clinical situations.
J Urol 191:1272–1279 Crouzet S, Chapelon JY, Rouvière O, Mege-Lechevallier F, Colombel M, Tonoli-Catez H, Martin X, Gelet A (2014) Whole-gland ablation of localized prostate cancer with high-intensity focused ultrasound: oncologic outcomes and morbidity in 1002 patients. Eur Urol 65:907–914 Crouzet S, Murat FJ, Pasticier G, Cassier P, Chapelon JY, Gelet A (2010a) High intensity focused ultrasound (HIFU) for prostate cancer: current clinical status, outcomes and future perspectives. Int J Hyperthermia 26:796–803 Crouzet S, Murat FJ, Pommier P, Poissonnier L, Pasticier G, Rouviere O, Chapelon JY, Rabilloud M, Belot A, Mège-Lechevallier F, Tonoli-Catez H, Martin X, Gelet A (2012) Locally recurrent prostate cancer after initial radiation therapy: early salvage high-intensity focused ultrasound improves oncologic outcomes.