101 Tips on Nutrition for People with Diabetes (2nd Edition) by Patti B. Geil, Lea Ann Holzmeister

By Patti B. Geil, Lea Ann Holzmeister

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In this new version, diabetes specialists Patti Geil and Lea Ann Holzmeister supply convenient tips about meal making plans, common food, dealing with drugs and food, purchasing and cooking, weightloss, and more.

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Additional info for 101 Tips on Nutrition for People with Diabetes (2nd Edition)

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REVISION NOTE: Modified to include review panel roster. INDIVIDUAL PROJECTS AND CORES PROJECT 1: Chemoprevention of Gastric Dysplasia: Long-term follow-up of a cohort treatment for H. H. Fontham, Dr. Generate_Screen Studies • 29 Project Title: HISTAMINE AND ASCORBATE IN ATHEROSCLEROSIS AND CHD Principal Investigator & Institution: Clejan, Sanda; Tulane University of Louisiana New Orleans, La New Orleans, La 70112 Timing: Fiscal Year 2001 Summary: The purpose of this project is to investigate the concentrations of histamine in whole blood and ascorbic acid in the blood plasma of normal unstressed people on a normal diet without dietary supplements, in people with unstable angina and in people with acute myocardial infarction, to test the hypothesis that histamine plays a key role in the development of atherosclerosis and coronary heart disease.

Increased degradation of nitric oxide by reactive oxygen radicals and inhibition of nitric oxide synthase via activation of protein kinase C are each potential mechanisms to account for decreased nitric oxide. The sponsor's laboratory has demonstrated impaired endothelium-dependent vasodilation in patients with diabetes mellitus and in healthy, nondiabetic subjects with experimental hyperglycemia. Further experiments showed that vitamin C improved endothelium-dependent vasodilation implicating a culpable role for superoxide.

D. It has continued to improve since the first review. One major exception was the validation of using PBL responses to reflect the immune and inflammatory status of leukocytes in the gastric mucosa. This was addressed satisfactorily in the accelerated peer review. The investigators responded by stating that for the first third of the patients analyzed (numbering 20), in vitro PBL responses will be compared with in situ gastric tissue responses. If concordance is observed, the remaining patients in the study will be followed as initially proposed, with concentration of efforts on PBL analysis.

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