Control of Chagas Disease: 2nd Report of the WHO Expert by WHO Technical Report Series

By WHO Technical Report Series

This record of a WHO specialist Committee reports present wisdom of Chagas affliction and its pathogenesis discusses the causative parasite the triatomine vectors and the typical reservoirs of an infection and considers the epidemiology and occurrence developments of the disorder. Prevention and keep watch over thoughts are defined as are a few of the formal projects for interruption of ailment transmission. The file concludes via picking priorities for examine and supplying counsel for the making plans implementation and strengthening of nationwide keep an eye on courses.

Show description

Read or Download Control of Chagas Disease: 2nd Report of the WHO Expert Committee on Chagas Disease (Technical Report Series) PDF

Best diseases books

Molecular Pathology of Liver Diseases

Molecular Pathology of Liver illnesses integrates the normal wisdom of physiological and pathological approaches within the liver with a balanced emphasis on primary ideas; well timed advances in mobile and molecular mechanisms; and utilized pathology. The textbook is prepared into numerous sections, every one of such as an array of chapters that gradually and cohesively problematic on pertinent liver biology and pathology.

Wildlife Diseases

The vast spectrum of subject matters lined within the 9 symposia and 4 open-paper classes of the 3rd Inter­ nationwide natural world disorder convention include a awesome number of principles and present examine info on ailments of natural world. The time period "wildlife" is huge in itself and is interpreted via the convention sponsor, The flora and fauna illness organization, to intend all free-living vertebrate and invertebrate participants of the animal nation.

Chronic pain and family : a clinical perspective

Persistent soreness impacts each aspect of a patient’s lifestyles, and nowhere is that this extra obtrusive than within the complicated area of relatives existence. continual discomfort and relatives: a medical point of view examines average kin matters linked to lengthy ailment, providing real looking how you can method them in remedy. trained through present perform and his personal adventure, famous author/clinician Ranjan Roy brings clean insights to universal discomfort eventualities and healing impasses, and gives a framework for assessing marital and family members relationships while persistent discomfort is a defining issue.

Extra info for Control of Chagas Disease: 2nd Report of the WHO Expert Committee on Chagas Disease (Technical Report Series)

Example text

2 The changes associated with domiciliation The domiciliation of triatomines is the main factor in increasing the risk of T. cruzi transmission to humans. g. multilocus enzyme electrophoresis (MLEE), DNA methods, or morphometrics, can help in elucidating the genetic and phenotypic changes associated with domiciliation. These techniques have shown that the process is usually associated with major migrations, the reduction of genetic repertoire, and increasing developmental instability, making the insect a more efficient vector as well as a more vulnerable target of control measures.

The main epidemiological applications of population genetics in triatomines are those concerned with systematics and studies of population structure. Population genetics focuses on genes, DNA fragments, or any trait considered to be a Mendelian factor, and their frequencies in various populations. Relevant techniques include the traditional MLEE and the more recent DNA methods. Analytical methods currently rely on certain probabilistic models defining genetic equilibrium. They delineate the expected features of genetic variability (heterozygosity) as well as of gene frequencies — or the frequency of DNA fragments — within and among populations.

Cruzi II with the domestic cycle, while T. cruzi I was preferentially encountered in the sylvatic environment (52). Since all parasites isolated from seropositive individuals from endemic regions belong to T. cruzi II, it is suggested that this group has properties that favour human infections and promote higher parasitaemia. On the other hand, in Amazonas, T. cruzi I was isolated from wild triatomines but from only a very small number of seropositive people with low parasitaemia and the indeterminate form of Chagas disease (52).

Download PDF sample

Rated 4.69 of 5 – based on 8 votes